OBJECTIVE： To explore clinical efficacy of mouse nerve growth factor to repair nerve damage in elderly electrical burn patients. METHODS： 78 elderly electrical burn patients were randomly divided into experimental group （40 cases） and control group （38 cases）. Both group received routine treatment， such as anti-infection and improve microcirculation etc； control group was additional given Vitamin B12 intramuscularly， 500 μg each time， qd； experimental group was additional given mouse nerve growth factor， 18 μg each time， qd； a treatment course lasted for 4 weeks， and both received 2 courses of treatment. The difference of neurological function score and nerve conduction velocity were compared between 2 groups before and after treatment； clinical efficacy and the occurrence of ADR were observed in 2 groups. RESULTS： Before treatment， there was no statistical significance in pinprick score， light touch score， sports scores， sensory nerve conduction velocity and motor nerve conduction velocity between 2 groups （P＞0.05）. After treatment， pinprick score， light touch score and sports scores of experimental group improved significantly compared to before treatment and control group， and sensory nerve conduction velocity and motor nerve conduction velocity increased significantly compared to before treatment and control group， with statistical significance （P＜0.05）. Total effective rate of trial group was 92.5％， which was higher than that of control group （63.2％）， with statistical significance （P＜0.05）. No obvious ADR was found in 2 groups. CONCLUSIONS： Intramuscular injection of mouse nerve growth factor to repair nerve damage in elderly electrical burn patients can not only improve neurological function score and nerve conduction velocity， but also can improve the clinical efficacy.