OBJECTIVE：To improve the quality standard of Shuangshen capsule. METHODS： TLC was conducted for the qualitative identification of Curcumnae radix and Rehmannia glutinosa in the preparation. HPLC was used for the content determination of salvianolic acid B in the preparation： the column was Diamonsil C18（2） with mobile phase of acetonitrile-0.1％ H3PO4（22 ∶ 78，V/V） at a flow rate of 0.5 ml/min， detection wavelength was 286 nm， column temperature was 30 ℃， and the injection volume was 2 μl. RESULTS： The TLC spots of C. radix and R. glutinosa were clear and well separated； the linear range of salvianolic acid B was 0.079 2-0.792 μg（r＝0.999 9）； RSDs of precision，stability and reproducibility tests were lower than 1％； recovery was 100.71％-101.82％（RSD＝0.50％，n＝6）. CONCLUSIONS：The established standard can be used for the quality control of Shuangshen capsule.