OBJECTIVE: To optimize the extraction of volatile oil from Atractylodes lancea and Citrus aurantium and inclusion technology of β-cyclodextrin (β-CD) in Heze granules. METHODS: The steam distillation method was adopted to extract volatile oil from Heze granules, and β-CD inclusion complex was prepared by aqueous solution method. The effects of the ratio of volatile oil to β-CD, the ratio of water volume to β-CD, inclusion temperature and mixing time on inclusion temperature were investigated by uniform design test to screen optimal technology, using the yield of inclusion complex and the yield of volatile oil as index. The inclusion complex was characterized with microscope, IR spectrum and UV spectrum. RESULTS: Optimum inclusion process was as follows as ratio of volatile oil to β-CD 1 ∶ 10 (ml/g), ratio of water to β-CD 10 ∶ 1 (ml/g), inclusion temperature 30 ℃,mixing time 3.5 h; the yield of inclusion complex was 73.06% and the yield of volatile oil was 96.24% (RSD≤5.43%, n=3). 3 characterization tests indicated that volatile oil had been included in β-CD. CONCLUSIONS: The extraction technology of volatile oil from A. lancea and C. aurantium and inclusion technology of β-CD in Heze granules are stable and feasible.