OBJECTIVE： To provide reference for the patent application of artificial cultivation and seed treatment technology of Paridis Rhizoma and natural resources protection. METHODS： Retrieved from State Intellectual Property Office patent database， “Paridis Rhizoma” and “Paris polyphylla” were used as search keywords from 1985 to March 31， 2015； Paridis Rhizoma cultivation and seed treatment technology patents as research object were analyzed in fields of the amount of patent application， regional construction and legal status， etc. RESULTS： Among 54 Paridis Rhizoma cultivation patent application， there were 19 applications from Yunnan， 9 from Sichuan， 8 from Hubei， 5 from Anhui， 4 from Hunan， 3 from Guizhou， 2 from Jiangxi， 1 from Fujian， Shanxi， Jiangsu， Guangxi respectively； there were 18 licensed patents， and 13 licensed patents maintained more than 3 years， among which 1 patent right transferred； from aspect of patent without right， 6 patent right were given up due to fail to pay annual fee， 1 rejected and 5 withdrawn； from main types of patent proposer， enterprise submitted 24 patent application， universities 15， scientific research institutes 8 and other 7. 24 enterprise patents involved 21 enterprises， indicating that patent protection net didn’t form due to disperse proposers. CONCLUSIONS： Patent application is mainly from Yunnan. There still are some problems， such as small number of patent applications， poor quality of application writing， little patent transformation. It is suggested to plan artificial cultivation technology， enhance the quality of patent application， pay attention to patent operation and achievement transformation and other measures， in order to protect Paridis Rhizoma resource and industrial development.