OBJECTIVE： To prepare Ferulic acid/K/β-CD/metal organic framework （FA/K/β-CD/MOF） inclusion， and to optimize its preparation technology. METHODS： K/β-CD/MOF was synthesized by solvothermal method as inclusion material. Using FA as main component， FA/K/β-CD/MOF was prepared by grinding method. The preparation technology was optimized by orthogonal test using mole ratio of main component-inclusion material， grinding time， dropping time and inclusion temperature as factors， inclusion rate as index. Prepared FA/K/β-CD/MOF was indentified by IR spectrum and DSC， and inclusion rate and dissolution rate were determined. RESULTS： Optimized preparation technology was as follows as mole ratio of main main component to inclusion material 3 ∶ 1， dropping time 60 min， inclusion temperature 40 ℃， inclusion time 60 min. Prepared FA/K/β-CD-MOF had already formed a new kind of phase， and its average inclusion rate was （18.0±1.6）％ （RSD＝0.9％， n＝6）； its solubility was 15 times as much as FA （9.582 mg/ml vs. 0.647 mg/ml）. CONCLUSIONS： FA/K/β-CD/MOF is prepared successfully； and the preparation technology is reasonable and feasible.