OBJECTIVE： To provide reference for rational use of TCM injection in patients receiving malignant breast tumor chemotherapy. METHODS： According to main disease diagnosis， 856 patients receiving malignant breast tumor chemotherapy were collected during Jan.-Sept. 2014 by using HIS， and then analyzed statistically in respects of irrational use of TCM injection， drug combination， ADR， etc. RESULTS： Of 856 patients， 572 patients received TCM injection， accounting for 66.83％； 11 kinds of TCM injections were involved. Irrational drug use mainly contained unsuitable dose （21.78％）， unsuitable solvent （31.06％）， unsuitable medication course （82.35％）， etc. Among TCM injection cases， there were 104 cases of combined use of 2 TCM injections （18.19％）， and 1 case of combined use of 3 kinds of TCM injection （0.12％）. A total of 8 cases of ADR occurred. CONCLUSIONS： Related regulation and management measures should be formulated， and prescribing behavior of physicians also should be standardized to to promote the rational use of TCM injections.