OBJECTIVE: To explore pharmaceutical care model provided by clinical pharmacists in neurology department under precision medicine system and the role of clinical pharmacists. METHODS: The practice and role of precision pharmaceutical care methods in neurology department were introduced
such as gene test technology
population pharmacokinetic model and individual plasma concentration monitoring. RESULTS: By using gene test technology
clinical pharmacists assisted clinical physicians to judge clinical efficacy of clopidogrel and develop individual dosing regimens of warfarin; predicted the dose of sodium valproate by using population pharmacokinetics; formulated individual medication guide by using blood concentration monitoring. Better clinical efficacy had been obtained and ADR reduced. CONCLUSIONS: Precision pharmaceutical care can effectively provide patients with optimal dosing regimens
predict initial dose and optimal therapeutic concentrations
improve efficacy and reduce ADR.
关键词
精准医疗神经内科精准药学服务
Keywords
Precision medicineNeurology departmentPrecision pharmaceutical care