OBJECTIVE：To evaluate the effect of clinical antibiotics use special rectification in our hospital. METHODS：100 discharged medical records of type Ⅰ incision surgery were randomly sampled from our hospital during May in 2010 to Apr. in 2011，May in 2011 to Apr. in 2012，May in 2012 to Apr. in 2013，May in 2013 to Apr. in 2014，totaling 400 records. And then evaluation indicators were analyzed statistically，such as antibiotics use intensity，perioperative DDDs of antibiotics in typeⅠincision surgery，DUI，types of antibiotics during perioperative period，medication time，etc. RESULTS：Since the implementation of clinical antibiotics use special rectification in May 2011，the utilization ratio of antibiotics in typeⅠincision surgery of our hospital decreased from 96％ to 33％；DUI decreased from 1.44 to 0.79；while reasonable rate of drug selection increased from 19.8％ to 100％，and that of medication time increased from 43.8％ to 100％. CONCLUSIONS：Rational medication evaluation indicators in typeⅠincision surgery of our hospital have been improved after the implementation of clinical antibiotics use special rectification.