OBJECTIVE：To establish the quality standard for ShutonganⅠgranule.METHODS：TLC was conducted for the qualitative identification of Citrus aurantium and Forsythia suspensa. HPLC was conducted for the content determination of naringin in the preparation；the column was Agilent C18 with mobile phase of acetonitrile-water（20 ∶80，V/V）at a flow rate of 1.0 ml/min，the detection wavelength was 283 nm，the column temperature was 30 ℃，and the injection volume was 10 μl. HPLC was also used for the content determination of phillyrin；the column was Agilent TC-C18 with mobile phase of acetonitrile - water（23 ∶77，V/V）at a flow rate of 1.0 ml/min，the detection wavelength was 277 nm，the column temperature was 30 ℃，and the injection volume was 10 μ l. RESULTS：The C. aurantium and F. suspensa of TLC showed clear spots and good separation. The linear range was 57.843-289.214 μg/ml for naringin（r＝0.999 9）and 37.434-187.169 μg/ml for phillyrin（r＝0.999 6）；RSDs of precision，stability and reproducibility tests were less than 2％；recoveries were 97.20％-102.04％（RSD＝1.7％，n＝9）and 97.14％-102.27％（RSD＝ 2.0％，n＝9），respectively. CONCLUSIONS：The standard can be used for the quality control of ShutonganⅠgranule.