OBJECTIVE：To investigate the effect of flurbiprofen on morphine doses and intestinal function recovery after radical gastrectomy for gastric cancer. METHODS：102 patients underwent radical gastrectomy of gastric cancer were randomly divided into control group and observation group，with 51 cases in each group. Control group was treated with routine morphine analgesia pump，and observation group was additionally given intravenous injection of flurbiprofen 50 mg before operation and 24 h after operation on the basis of control group. VAS，comfort score（BCS），the amount of morphine and intestinal function recovery were observed and recorded in 2 groups. RESULTS：48 h after operation，there was no statistical significance in VAS and BCS scores between both groups（P＞0.05），but the dose of morphine in observation group was significantly less than in control group，with statistical significance （P＜0.05）；the postoperative recovery time of bowel sounds and the first anal exhaust time in observation group were significantly shorter than control group，and the incidence of nausea and vomiting in observation group was significantly lower than control group，with statistical significance（P＜0.05）. CONCLUSIONS：The application of flurbiprofen combined with morphine in gastrectomy can reduce the dose and ADR of morphine based on the same analgesic effect，and it is good for the recovery of intestinal function.