OBJECTIVE：To investigate the role of medication reconciliation in pharmaceutical care provided by clinical pharmacists. METHODS：Clinical pharmacists participated in pharmaceutical care for a elderly patient，and reconciled drugs as anti-infective drugs，cardiovascular drugs，electrolyte：stop taking unnecessary drugs：Xuebijing injection，Kang’erxin capsule，Shedan chuanbei soft capsule，Mosapride citrate tablet；adjust the dose of Dihydrochlorothiazide tabet and Potassium chloride tablet；stop taking Non first-line drug Reserpine tablet in order to decrease the risk of drug use； stop taking Furosemide tablet，Lactulose oral solution and using Suppositories glycerol timely according to the disease outcome. RESULTS&CONCLUSIONS：The medication reconciliation can avoid repeated drug use，optimize medication plan，reduce drug variety and cost and decrease the potential ADR risk of drug use so as to guarantee safe and effective drug use.