OBJECTIVE：To investigate the application effect of PDCA circulation method in clinical pharmaceutical care. METHODS：According to the method of PDCA cycle，clinical pharmaceutical care quality and satisfaction degree of physicians， nurses and patients in 2013 were investigated to find out the problems；the reasons were analyzed and countermeasures were made out，checked and implemented. Finally，the quality of clinical pharmaceutical care，the medical staff and patient’s satisfaction with clinical pharmaceutical care were compared before and after the implementation of PDCA circulation. RESULTS：Due to the poor quality of clinical pharmaceutical care and low satisfactory degree of our hospital，we formulated related countermeasures，such as enhancing the medication service skill of clinical pharmacists in obstetrics and gynecology department，extending the coverage of pharmaceutical ward round，developing the pharmaceutical care for patients with high risk pregnancy or underwent assisted reproduction， strengthening communication and propaganda of medical staff and patients. After the implementation of countermeasures， the quality indicators of clinical pharmaceutical care were improved in 2014，compared to 2013，such as the number of patients included in pharmaceutical ward round increased from 445 to 1 780；total number of reasonable medication intervention suggestion increased from 14 to 29；that of pharmaceutical consultation increased from 8 to 23；the satisfaction degree of medical staff and patients improved from 55.93％ and 45.95％ to 100％ and 92.10％，respectively. CONCLUSIONS：PDCA circulation can significantly improve the quality of clinical pharmaceutical care and satisfactory degree of our hospital，and promote pharmaceutical care of our hospital.