OBJECTIVE：To explore the role of clinical pharmacist in the therapy for patient with community-acquired Pseudomonas aeruginosa lung abscess. METHODS：Clinical pharmacist participated in the therapy for a patient with community-acquired P. aeruginosa lung abscess，analyzed anti-infective therapy plan，and adjusted drug use timely to correct agranulocytosis induced by anti-infective drugs. RESULTS：The physicians adopted the suggestions of clinical pharmacists，controlled the infection successfully and corrected agranulocytosis. CONCLUSIONS：Community-acquired P. aeruginosa lung abscess is rare but has high mortality. Clinical pharmacists participate in drug therapy，assist physician to improve and optimize therapy plan and formulate individual medication plan so as to promote promote care rate of patients.