OBJECTIVE：To investigate the role of clinical pharmacists in the therapy for patient with multiple pulmonary infection after renal transplantation. METHODS：Clinical pharmacists participated in drug therapy for a patient with multiple pulmonary infection after renal transplantation，and assisted physicians to formulate primary therapy plan：ganciclovir 250 mg，ivgtt，q12 h+ Cefoperazone sodium and sulbactam sodium 3 g，ivgtt，bid+ methylprednisolone 80 mg，ivgtt，qd+ Compound sulfamethoxazole tablet，2 piece，po，qd+Ciclosporin soft capsule 75 mg，po，q12 h+Sodium bicarbonate tablet 1 g，po，qd+Nifedipine controlled release tablet 30 mg，po，qd+Famotidine tablet 20 mg，po，bid. The dose of ganciclovir was adjusted twice because of complication cytomegaloviral pneumonia；the dose of ganciclovir was adjusted twice because of complication pneumocystis pneumonia. Prevention and disposal of ADR，patient education were also conducted. RESULTS：Physicians adopted the suggestion of clinical pharmacists； the pulmonary infection had been controlled，and the patient was discharged from hospital. CONCLUSIONS：Clinical pharmacists identify the breakthrough point to promote rational drug use，indicating the value of pharmaceutical care in the clinical treatment.