OBJECTIVE： To provide reference for rational use of respiratory system drugs. METHODS： The utilization of respiratory system drugs in our hospital during 2011-2014 was analyzed statistically in respects of drug types， consumption sum， DDDs， etc. Top 20 drugs in the list of DDDs was analyzed by using drug utilization study. RESULTS： During 4 years， categories， consumption sum ratios and DDDs ratios of respiratory system drugs showed a stable tendency. The types， consumption sum and DDDs ratios of TCM preparations had dominated the first places for 4 years， while antitussive was always the last one. The DDDs ratios of antiasthma increased from 17.06％ to 24.68％ during 2011-2014. Antiasthma had dominated the important place in respiratory system drugs. Top 10 drugs in the list of DDDs were Ambroxol injection， Budesonide and formoterol fumarate powder for inhalation， Levocetirizine dihydrochloride tablets/dispersible tablets/oral solution，Jinshuibao capsules，Budesonide suspension for inhalation. Among them， DDDs of Ambroxol injection was increasing year by year and ranked first every year. CONCLUSIONS： It shows a stable tendency in the use of respiratory system drugs. TCM preparations have occupied the most important position among respiratory system drugs， while antitussive show a fading trend. Antiasthma take up a more and more important position. However， we should pay more attention to the overuse of Ambroxol injection.