OBJECTIVE：To investigate new thought and method for improving the practice teaching effect of pharmacy undergraduates under the collaboration of medicine and education. METHODS：The training objectives of pharmacist team，the current situations and problems of teaching that existing in the institute of pharmacy and the requirement of talents in the work were summarized and investigated，and then reform targets and measures were put forward. RESULTS：Training for pharmacists tream gradually movedcloser to clinical pharmacists in China.The teaching work in the pharmacy department of our hospital was relatively complete， including relevant teaching system，practice systems and processes，training program for clinical pharmacists and development of workflow；however，there still remained some problems，including lacking of professional quality training，suitable courses， effective interactive medical and education scientific assessment mode and no attention for the training of clinical thinking and school-university research thinking. The above-mentioned problems needed to be solved by reforming internship tutorial system and improving the contents，establishing the school-hospital united system，emphasizing the connection between schools and teaching bases，establishing integrated teaching evaluation system and assessment criteria，strengthening clinical experience and training for clinical thinking by the teaching mode of physicians and pharmacists. CONCLUSIONS：Strengthening the collaboration of medicine and education and improving the training standards and evaluation system are helpful for improving the practice teaching quality of pharmacy undergraduates.